Brandon Aiyuk looked like he was well on his way to a WR1-caliber season after a dominant opening game, but a shoulder injury suffered early last week limited his snaps and production. With a quick turnaround for Thursday Night Football matchup against the Giants, Aiyuk is in danger of sitting out Week 3. He's a must-start if he plays, so knowing the latest updates will be important ahead of one of your first start 'em, sit 'em decisions of the week.We'll continue to update this article with news on Aiyuk until the official active/inactive report comes out on Thursday around 6:50 p. Tony Carr Jersey m. ET.MORE THURSDAY NIGHT FOOTBALL: | | | | UPDATE 9/20:Aiyuk is officially listed as "questionable" for Thursday night,.Shanahan also confirmed that the receiver will be a game-time decision.UPDATE 9/21:ESPN's Adam Schefter reported late Thursday afternoon that Aiyuk is "" on Thursday night against New York.UPDATE 9/21:Aiyuk (shoulder) has been ruled out for Week 3, according to the .According to 49ers' general manager John Lynch, we'll have to wait and see whether Aiyuk suits up for "Thursday Night Football." Lynch said on KNBR, a local radio station in the Bay Area, that the receiver would Frank Jackson Jersey be a game-time decision with a shoulder injury."He's working really hard to try and get ready," . "With these Thursday night games, you take it all the way down to kickoff ."WEEK 3 PPR RANKINGS: | | | | | If Aiyuk does end up playing, Brandon Ingram Jersey he's a must-start. He's been targeted 14 times in two weeks despite suffering the injury early on Sunday against the Rams. He's become a reliable weapon for Brock Purdy and should continue to be as long as he stays on the field. The matchup with the Giants looming on Thursday night should have Aiyuk's eyes wide open after seeing how their defense has been torched thus far in 2023. CeeDee Lamb wreaked havoc on them in Week 1, recording 77 yards on four catches despite Dak Prescott completing just 13 pa ses. The Cardinals diced up that same defense in Week 2 with Josh Dobbs throwing for 228 yards despite not being known for his arm.WEEK 3 STANDARD RANKINGS: | | | | | However, if Aiyuk sits out, we can expect Kyle Shanahan to turn to Jauan Jennings or Ray-Ray McCloud III to try and help fill that void. In addition, it also means an upgrade for Deebo Samuel and George Kittle in the pa sing game, as well as RB Elijah Mitchell, who's due to see more snaps. In the case of Mitchell, Shanahan could opt to use Christian McCaffrey and Mitchell in two-back sets Jrue Holiday Jersey , but fantasy owners who roster Aiyuk might want to look elsewhere for a replacement if he's declared out.At this point in the season, all 32 teams are still in action, and that means you should have options on your bench. If not, Jennings is the preferred Anthony Davis Jersey choice that's widely available in the San Francisco offense. Otherwise, pickings are getting slimmer on the open market, with leading options on the waiver wire including Rashid Shaheed (@ Packers), Josh Reynolds (vs. Falcons), and Tutu Atwell (@ Bengals). They are all available in over 50 percent of Yahoo leagues and should be your first look for options outside of the 49ers roster. If Christian Watson (hamstring) doesn't play for the Packers again this week, Romeo Doubs and Jayden Reed (both vs. Saints) catapult back into consideration as flex options or receiver replacements.